Publications & News

June 2023- Read Randy Seeley's and Samuel Klein's discussion on... 

Weight versus weight-independent effects of Roux-en-Y gastric bypass on type 2 diabetes 

Published online in Nature Metabolism: Click Here!

October 13, 2022 - Cell Metabolism
Jae Hoon Shin, Nadejda Bozadjieva-Kramer, Yikai Shao, Sally Lyons-Abbott, Alan C. Rupp, Darleen A. Sandoval, Randy J. Seeley

View this article here!

Weight Loss Independent vs Dependent Effects of Bariatric Surgery Debate

At the CDI-MOD Symposium in May 2022 Sam Klein, MD and Randy Seeley, PhD, debated the question: Does bariatric surgery contribute to metabolic changes beyond those associated with weight loss?
Watch video here! 

Who knew? PPARs may act in the brain too

August 22, 2022 - Nature Metabolism Publication by Randy Seeley and Christopher Rhodes 

View this article here!

June 14, 2022- CBMR at the University of Copenhagen

Dr. Randy Seeley discusses what bariatric surgery tells us about the role of the gut in metabolism in Copenhagen, watch his talk here!

Congratulations Dr. Nadejda Bozadjieva Kramer!

Dr. Nadia is now a research investigator at the VA Ann Arbor and University of Michigan!

Research Assistant Professor

University of Michigan

Department of Surgery

2800 Plymouth Road, B20-201W

Ann Arbor, Michigan 48109


Research Biologist

LTC Charles S. Kettles VA Medical Center

Research Service

Ann Arbor, Michigan 48105

New publications from previous members... 

January 2022- Simon Evers and Yikai Shao recent papers:

Gut HIF2α signaling is increased after VSG, and gut activation of HIF2α decreases weight, improves glucose, and increases GLP-1 secretion.

Evers SS, Shao Y, Ramakrishnan SK, Shin JH, Bozadjieva-Kramer N, Irmler M, Stemmer K, Sandoval DA, Shah YM, Seeley RJ.Cell Rep. 2022 Jan 18;38(3):110270. doi: 10.1016/j.celrep.2021.110270.PMID: 35045308


Vertical sleeve gastrectomy increases duodenal Lactobacillus spp. richness associated with the activation of intestinal HIF2α signaling and metabolic benefits.

Shao Y, Evers SS, Shin JH, Ramakrishnan SK, Bozadjieva-Kramer N, Yao Q, Shah YM, Sandoval DA, Seeley RJ.Mol Metab. 2022 Jan 6;57:101432. doi: 10.1016/j.molmet.2022.101432. Online ahead of print.PMID: 34998940 Free article.

Congratulations Dr. Anita Patel!

December 15, 2020 - Anita Patel completed her PhD defense 

  LPS induces rapid increase in GDF15 levels in mice, rats, and humans but is not required for anorexia in mice.

Patel AR, Frikke-Schmidt H, Bezy O, Sabatini PV, Rittig N, Jessen N, Myers MG Jr, Seeley RJ.Am J Physiol Gastrointest Liver Physiol. 2022 Feb 1;322(2):G247-G255. doi: 10.1152/ajpgi.00146.2021. Epub 2021 Dec 22.PMID: 34935522

Dr. Sandoval moved to Colorado!  

September 01, 2020 - Darleen Sandoval accepted a new position as Professor of Pediatrics at the University of Colorado Anschutz Medical Campus

Congratulations Darleen!

Lab Report: Michigan Medicine Health Lab 

January 17, 2020 - A blog published for the U-M Health Lab regarding the Cell Metabolism study involving  Drs. Seeley and Myers, check it out here!   

A CALCR cell found in mice may stop feeding without subsequential nauseating effects as well as influence the long term intake of food.


Randy is interviewed on Weight Loss Surgery Podcast- Again!

Listen to Geeking Out on Bile, Bugs, and Bariatric Surgery with Randy Seeley, PhD 

December 2, 2019 - Randy Seeley is interviewed on the Weight Loss Surgery Podcast hosted by Reeger Cortell, FNP-C.

"In this episode I welcome back research scientists, Dr. Randy Seeley. Dr Seeley is a Professor of Surgery, Internal Medicine, and Nutritional Science at the University of Michigan. In this episode we discuss bile acid metabolism, the gut microbiome, sleep apnea and the gut, and iron metabolism."

Congrats, Ki!

November 11,  2018 - Dr. Ki Suk Kim is a finalist for the 2018 Ethan Sims Young Investigator Award. He will be competing against 5 other finalists for the award as part of Obesity Week, on Thursday 11/15 in Nashville, TN. The Sandoval and Seeley labs are so proud of Ki's achievements! If you are attending ObesityWeek 2018 this year, be sure to attend Ki's session!


Congrats, Bailey!

November 9, 2018 - Dr. Bailey Peck has accepted a Medical Science Liaison position at Shire Pharmaceuticals in their GI Unit.  She will be ending her NIH NRSA Fellowship and leaving the Seeley & Sandoval labs in November. We are sad to see her go, but excited for her new career opportunity!

Aug 31, 2018 - Dr. Bailey Peck receives a 2-year F32 NRSA Postdoctoral Fellowship awarded by NIDDK. Her proposed research focuses on understanding the role of non-coding RNAs in extracellular vesicles in the intestinal mucus in mediating response to bariatric surgery. Go Team SLiME!

 Congrats, Chelsea!

July 1, 2018 - Dr. Chelsea Hutch begins 3-year American Diabetes Association Postdoctoral Fellowship, which she was awarded last December. Chelsea's research focuses on sex differences in response to bariatric surgery.

 Congrats, Elika!

July 1, 2018 - Dr. Elika Ridelman has accepted a Research Associate position at Children's Hospital of Michigan & Wayne State University. She will also be serving as an Adjunct Professor at Lawrence Technological University.

Landon & Darleen are featured in Molecular Metabolism!

 May 22, 2018 - Undergraduate & now Master's student Landon Wood published in Molecular Metabolism last February. Their video abstract was recently featured by Molecular Metabolism!

Check out their Video on Twitter

 Congrats, Deanna!

Dr. Deanna Arble has accepted an Assistant Professorship at Marquette University in Milwaukee, WI. She will be leaving the Seeley and Sandoval labs to start her own lab investigating sleep apnea, circadian rhythm, and metabolism in Fall 2017.

Check Out Deanna's Lab Homepage

Congrats, Darleen!

May 18, 2017 - Dr. Darleen Sandoval is promoted to Associate Professor of Surgery, with TENURE, and Associate Professor of Internal Medicine.

Check out the report in the University Record.

Randy is interviewed on Weight Loss Surgery Podcast

056 Randy Seeley, PhD: The Biology of Body Weight

July 17, 2015 - Randy Seeley is interviewed on the Weight Loss Surgery Podcast hosted by Reeger Cortell, FNP-C.

Listen to it here!